A high spinal cord injury in the neck can prevent people from properly using their arms and hands. As a result, it becomes difficult to use computers and other digital devices. This has major consequences for communication and independence, and limits these individuals’ ability to benefit from the opportunities that digital devices offer.

Assistive technologies currently available for operating digital devices do not provide a good solution for everyone. They are often difficult to use, slow, limited in functionality, unattractive, and can interfere with normal movement or speech.

At the department of Neurology and Neurosurgery at UMC Utrecht, research is being conducted on controlling digital devices using brain signals. Previous studies have shown that controlling devices with brain signals is possible, but that speed still needs to be improved. The INTENSE study investigates whether controlling digital devices via brain signals can be made faster and more effective using a new type of brain implant. We also want to test whether learning to use this control method can be accelerated by applying brief electrical stimulation to the area of the brain responsible for sensation in the hand.

The INTENSE study lasts approximately one year, although an extension is possible. We will first conduct a number of tests to determine whether you are eligible to participate in this study, such as a functional MRI scan. If you are eligible, a small electrode array will be placed on your brain during surgery at UMC Utrecht. This array is connected via short wires to a device (the amplifier/transmitter) that is positioned on the skull but beneath the skin. This device contains a magnet that allows a receiver to be placed on the scalp and remain in position. The brain signals are transmitted wirelessly through the scalp, from the amplifier/transmitter to the receiver. The receiver is connected to a computer via a cable.

Once you have returned home, you will be visited regularly by the research team. During these visits, we will measure the brain signals and provide training on how to use the INTENSE system.

Suitable candidates are between 18 and 70 years old, have a high-level spinal cord injury and are therefore paralyzed, with difficulty using their arms and hands. Participants are still able to speak and do not have an intellectual disability.

Are you interested in participating, or do you know someone who might be? Please contact our research team at neuroprothese @ umcutrecht.nl, or fill out the contact form via the link below.